What is Kryptopyrrolurea?
Kryptopyrrolurea is a genetically
determined, metabolic disorder, often occuring as a biochemical-enzymatic familiarly during the chemical reaction of formation of the
red blood pigment. (Hemosynthesis).
It can be said that
Kryptopyrrolurea is not a symptom, but rather the primal cause for
different symptoms and disease states.
In the German-speaking
countries, Kryptopyrrolurea is abbreviated as KPU.
In the Netherlands HPU. In the Anglo-American world, Pyrrolurea is
also called Malvurea or Malvaria, because the pyrrole in the urine
has a malvene-like colouration. (Malvene factor in the urine).
the abbreviation is : HPL = Hemopyrrole. The KPU is a concept from
biochemistry. The word Krypto is derived from the Greek Krypta and means
hidden. Pyrroles are building blocks of red blood pigments and certain blood
proteins. When blood ages, pyrrole appears as a component of bile acids in
the stool and gives it a brown colouration. In the case of pyrrolic persons the
amount of pyrrole in the blood is increased and therefore it appears in
the urine. Urea means that pyrrole is not only excreted via the stool but
also through the kidneys in the urine as well.
The diagnosis of Kryptopyrrolurea means for the physician:
- that the evidence of an abnormally increased excretion of pyrrole
(Malvene factor) in the urine occurs. This can be given the highly
probable diagnosis of Kryptopyrrolurea.
This substance is
detected in everybody´s excretions. If the amounts are higher than 10
microgramms per deciliter in the urine however, then there are
corresponding subsequent damages, which follow Kryptopyrrolurea and
are no longer possible to be avoided.
- that vitamine B6 and zinc are increasingly excreted via the urine.
The evidence, whether vitamine B6 and zinc are available in the cell,
can be obtained by an intracellular blood analysis. Seral analyses in
this case do not reveal the true picture.
- that the physician can clarify, whether subsequent damages have already occured and
whether these must be healed in the first place by the treatment of
the primary cause of the disease, in this case the KPU, by providing
substitutes of vitamine B6 zinc and eventually other minerals. Here,
the cooperation of the patient is demanded, because in the majority
of cases an
alteration of nutritional habits is necessary.
What does the diagnosis of Kryptopyrrolurea mean for the patient?:
- The vitamine B6 and zinc deficit are an indication of the fact, that
the person is not able to detoxify his/her body. In the cells there is a
life-long chronic deficit on vitamine B6 and zinc, which can not be
replenished by a normal healthy varied nutrition.
- toxic substances, either produced by the body or taken in by nutrition or by the
environment, such as e.g. alcohol, nikotine and drugs, can not be
processed, which in turn during the course of life can lead to more
severe disease signs.
- the body is not able to detoxify pesticides and diverse chemical
additives present in our current modern nutrition, exactly like the toxic
substances, that are inspired by the bronchiae, such as e.g: chemicals in
the household and in the work-place, among others cosmetics, cleaning
liquids and detergents, evaporations of pieces of furniture,
carpets, colouring agents, etc., which are still nowadays often
polluted with formaldehyde, as well as perchlorethylene from the chemical
toxic residues in new cars.
- Apart from these: moulds, chlorine (indoor swimming pools, paper bleached with chlorine),
environmental pollution such as smog, car exhaust fumes, high ozone
amounts, can cause problems. Even many vaccines can be a problem for the pyrrolic
person, who is not being administered additional vitamine 6 and zinc.
- Toxic local anaesthetics can not be tolerated.
- In many cases there exists an intolerance to medication
Consequently, a diagnosis of
Kryptopyrrolurea means for the patient: change of nutritional habits,
intake of nutrition supplements, resulting in higher resistance to toxic
substances and detoxification.
The history of KPU
The first indications of pyrrole in the urine go as far
back as the year 1894. Research documents prove, that
the northern American scientists Irvine and O’Reilly as far as fifty
years ago were searching for biochemical factors, which could explain psychic
disease symptoms. Indisputable studies about Kryptopyrrolurea have
already existed for the last 20 years. Except Irvine and O’Reilly, other
scientists had already discovered KPU and published articles about psychiatry
patients suffering from this disease.
As early as almost twenty years ago, Dr. rer. nat. Dr. med. Carl C.
Pfeiffer published in his “Golden Pamphlet” (Nutritional
therapy by psychic disorders) the probably most extensive discoveries,
which were firstly published in German language by the Haug Verlag in 1986 (Editions
Haug) (look also: “Orthomolecular medicine”
and “Research and references in literature”).This book appeared in 4
1989, 1990, 1993. In the last 10 years however, there was not much
heard about KPU. The renowned publisher for alternative medicine was
taken over in 1999 by the Medical School Editions Thieme Verlag and the
above-mentioned book, nowadays more interesting than ever, was not
printed in a new edition any more. A newly revised edition would not be
addressing the layman, but rather would be above all important for the
treating physician. Unfortunately, apart from this book there is almost
no relevant literature, upon whose information patients could be
informed and only a few possibilities in form of seminars exist, in
which physicians could be further trained.
My own, first experiences during the laborious research to the question: What is Kryptopyrrolurea? What is a pyrrolic person?
As Dr. Bodo Kuklinski explained to me in August 2000: “You are not
suffering from an allergy – you are a pyrrolic person”, I searched
immediately afterwards in the largest book-store in the area to look this
term up. I looked it up in Pschyrembel and looked through several dictionaries.
Everywhere dead end. Neither under the term kryptopyrrolurea nor under
pyrrolurea or pyrrolic could I find an entry. Later, I tried to find some
evidence for the first time at an internet café. I tried various search machines.
Nothing. Finally I came up with the idea, to search internationally. At an
English - language internet site I finally discovered what I was
looking for. But then I reacted with astonishment and scepticism at the
same time: because kryptopyrrolurea was exclusively mentioned in
combination with the concepts autistic behaviour, epilepsy, schizophrenia, manic- depressive
activity and with the symptom of hyperactivity of children, at that
time still unknown to me.
This frightened me. What was I dealing with?
It is a good feeling to
notice that today, thanks to the internet there are many more entries
Finally there is movement in this direction. I wish that even more
people would find out more about this phenomenon, which, if diagnosed early
enough, can be treated very well and with a high degree of succes with
the easiest means of the orthomolecular medicine and the nutrition
supplementary products, that are nowadays questioned for their effectivity. I wish that many people have a knowledge about the fact how sustainably
effective their various health problems could be solved. But above all
it would be desirable that school children would be supported in their
learning process in the future in such a way, that they would not be
disadvantaged due to their inborn unusual constitution.